Has anyone here experienced De Quervain's tenosynovitis at all? It's s the inflammation of the sheath, or synovium, that surrounds the two tendons that run between the wrist and the thumb. I have been suffering from it since before my babies birth and that is now 12 months ago. I have tried splinting and physio but no real relief. It is getting very bad and making it difficult to work. Any suggestions greatly appreciated.